Legit.Health · Clinical Trials Platform
AI-Powered Dermatology
for Clinical Trials
Accelerating precision dermatology with automated scoring and decentralized imaging. Standardize your endpoints with clinical AI.
Why Legit.Health for Clinical Trials
📊
Novel Digital Endpoints
Increase the quantity of endpoints with the ability to extract data from photos automatically
🔍
Image Quality and Positioning Validation
AI analyses the quality and clinical utility of images to ensure their quality via control of focus, lighting, etc.
📁
Data Export
Extracts clinical data from images and exports it to readable formats such as CSV, XLS, or JSON
AI Photo Service Provider
Artificial Intelligence Inside the Protocol
Legit.Health is integrated directly into your study protocol as a photo service provider. The AI analyses every image, fills in severity scores automatically, validates image quality, and exports structured clinical data — increasing the number of measurable endpoints while removing manual reviewer burden.
Image Quality Validation
Automated checks for focus, lighting, framing, and clinical utility reject sub-standard images before they enter the trial database.
Automatic Score Computation
AI reads each image and fills in PASI, SCORAD, SALT, and other indices automatically — no manual investigator calculation required.
Novel Digital Endpoints
Digital photography unlocks measurable endpoints — lesion area, colour, texture, spread — that are impossible to quantify manually.
Data Transfers (CSV · JSON)
All extracted clinical data is transferred in structured formats for direct integration into your EDC or statistical analysis pipeline.
Dermatology Research Context
Challenges Solved by AI Photography
✕Challenges in Dermatology Studies
- —Investigators must manually quantify skin lesions
- —Local skin reactions are subjectively evaluated
- —Tedious assessments reduce investigator adherence
- —Lack of standard conditions for clinical observations
- —Difficulty measuring the treatment area with accuracy
- —Problems locating the treatment area precisely over time
✓AI Digital Photography Opportunities
- ✓Reduce inter- and intra-observer variability
- ✓Precise, reproducible location of the treatment area
- ✓Automatic calculations of skin lesion metrics
- ✓Time-saving during clinical assessments
- ✓Novel endpoints based on digital photography
- ✓Robust, documented digital process throughout the study
- ✓Enables teledermatology and remote data capture
Conditions Supported
Built for Dermatology
Each condition has a validated scoring system, standardized perspectives, and an imaging mode designed for the study context.
Psoriasis
APASIAlopecia
ASALTAcne
ALADINAtopic Dermatitis
ASCORADWounds
AWOSIVitiligo
AVASIHidradenitis Suppurativa
AiHS4Urticaria
UAS7Additional indicators
Available on requestCore AI Modules
Under-the-Hood Intelligence
Five specialised AI modules work together to validate, segment, and analyse every image captured during the trial.
Dermatology Image Quality Assessment (DIQA)
Validates focus, lighting, and framing; rejects clinically unusable images before they reach the database.
Body Surface Area (BSA) Pose Validation
Confirms captured images belong to expected anatomical domains (scalp, face, trunk, etc.).
Available upon requestBody Surface Segmentation
Identifies and segments body regions for consistent BSA calculations across visits.
Available upon requestSkin Surface Segmentation
Isolates skin surface from background and clothing for precise lesion localisation.
Available upon requestLesion Segmentation
Delineates lesion boundaries at pixel-level accuracy to compute area, colour, and texture metrics.
Imaging Modes
Capture Where It Makes Sense
Choose the imaging mode that fits your protocol — or combine both for maximum flexibility.
Decentralized
Subjects capture images from home using a guided mobile UI — no clinic visit required. Ideal for studies prioritising patient convenience and real-world data.
In-clinic
Site staff capture images during scheduled visits using clinic devices. Best for protocols requiring controlled lighting, standardised equipment, or immediate QC review.
Data Protection
🔒 Anonymization & Privacy
All images are anonymised before transfer. Multiple privacy layers ensure regulatory compliance and protect subject identity.
Pre-transfer Anonymisation
All identifiers stripped before images leave the platform.
Automatic Background Blur
AI removes environmental context that could identify location.
Facial Redaction
Eyes and mouth automatically detected and obscured.
Tattoo Redaction
Identifying marks detected and blurred to prevent re-identification.
HIPAA-Compliant
Full compliance with HIPAA and GDPR data protection requirements.
How It Works
3-Phase Workflow
Phase 01
Capture
- ✓Decentralized or in-clinic image collection
- ✓Real-time AI quality control
- ✓Guided pose detection overlays
- ✓11-perspective full-body or scalp/face capture
Phase 02
Intelligence
- ✓Automated severity scoring (APASI / ASALT / ALADIN)
- ✓No manual review required
- ✓Longitudinal tracking across visits
- ✓Blinded image handling for site staff
Phase 03
Control
- ✓Background blur + facial redaction pipeline
- ✓Sponsor Looker Studio dashboard
- ✓Deviation digest emails per site
- ✓Formal Data Transfer Agreement (DTA)
Platform Features
Everything You Need, Built In
Decentralized Imaging Capture
Subjects capture images from home using a guided mobile UI — no clinic visit needed.
Automatic Image Quality Control
AI rejects blurry, poorly lit, or misframed images in real time before upload.
Automatic Pose Detection
Overlay templates guide subjects and staff to reproduce standardized perspectives visit-over-visit.
AI Severity Assessment
Fully automated scoring using validated dermatology indices — results available instantly.
Anonymization & Privacy (HIPAA)
All exported images are anonymized: background blurred, faces redacted, metadata stripped.
Multi-language (14 Locales)
Full UI and investigator manual translation for en-US, es-ES, de-DE, fr-CA, and 10 more.
User Journeys
Different Roles, One Platform
Step-by-step workflows for every stakeholder in the trial.
Role 01
Site Staff
Enrol Subject
Add subject with site code (CV5-CC#####) and subject code after ICF is signed; system sends activation email automatically.
Configure Profile & Language
Set language — cascades to all subjects created thereafter across 14 locales.
Manage Subjects
View upload history per subject to confirm protocol compliance; image content is hidden to maintain blinding.
Track Deviations
Receive daily digest emails listing subjects with missed or late timepoints; follow up and document retraining in source docs.
Handle Termination (Admins only)
Request final image set → terminate subject → access revoked, data retained per 21 CFR 312.62(b).
Role 02
Subject
Activate Account
Receive email invite → set password (8+ chars, uppercase, lowercase, number, special char) → add app to phone home screen.
Configure Phone
Access clinicaltrials.legit.health on mobile, follow setup wizard, ensure device is charged.
Capture 11 Images
7 full-body perspectives + 4 close-up lesion images guided by overlay templates; app validates quality and pose in real time.
Review & Crop
Preview each image, optionally crop to remove background, confirm before upload.
Submit
Upload all 11 images together; do not close or refresh; success confirmation shown (images not visible to subject).
Repeat per Visit
Personalized schedule anchored to first upload date; site staff notified automatically if windows are missed.
Role 03
CRO / Sponsor
Request Dashboard Access
Submit a file to Legit.Health with user list, named "YYYY-MM-DD Request for access to Legit.Health Dashboard | Who will see data | v.X.X".
Receive Credentials
Legit.Health assigns a unique password per user and sends credentials via email with a direct dashboard link.
Monitor Trial in Real Time
Access Looker Studio dashboard (password-protected, sponsor-only) with real-time metrics by site, patient enrollment status, and image capture compliance.
Review Deviations
Track protocol deviations across all sites with full audit trail; site staff handle follow-up, sponsor has full visibility.
Data Transfer
Receive monthly anonymized image exports (background blur + facial redaction) via DTA; final transfer at study close.
Multilingual Investigator Manual — Included
Every trial gets a dedicated, versioned web manual with screenshots and instructions for site staff and subjects, translated into 14 languages. View the demo manual to see it in action.
Ready to Deploy?
Reach out to start configuring your trial — scoring system, locales, imaging mode, and manual, all in one platform.